Azumanga Daioh (2002)

Chiyo Mihama, a ten-year-old genius, struggles to blend in with her high school peers, who are all five years older. Her classmates include the quirky Osaka, whose unusual perspective often leaves others baffled; the fiery Tomo, known for her explosive energy; the athletic and competitive Kagura; the quick-tempered Yomi; and the shy Sakaki, who has an unwavering affection for animals that remains unreturned. Alongside their teacher, this eclectic group experiences the ups and downs of high school life, filled with laughter and challenges that foster lasting friendships.