Johnny Test (2005)

Johnny is an adventurous young boy brimming with enthusiasm. His ingenious twin sisters, Susan and Mary, often enlist him as the test subject for their wild scientific experiments. Whatever their imaginations conjure, Johnny is ready to dive in—provided his genetically enhanced dog, Dukey, can join the fun. Each episode showcases their zany inventions and the chaos that ensues, highlighting Johnny's bravery and the unique bond he shares with his sisters and loyal companion.